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HPLC Method Development for Pharmaceuticals (Separation Science and Technology, Volume 8) Satinder Ahuja, Henrik Rasmussen
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Review

Review in Doody's 2008, by Joseph Boullata, PharmD(University of Pennsylvania College of Nursing):

"This book is written with pharmaceutical scientists in mind, regardless of their level of experience with HPLC method development. By extension, it would be valuable for managers and regulators as well. It may also be of value to those managing a lab or research program in the academic setting.

The 18 chapters are written by 35 contributors, mostly from the U.S., with just over half from the pharmaceutical industry. The book is divided into two major sections, one a state-of-the-science review of HPLC and one on the unique needs in a pharmaceutical setting. This latter section is what makes the book most useful to the intended audience. It addresses topics such as method development for each phase in the drug development process, strategies for software/hardware validation, and prevention/troubleshooting problems. There is lots of concern for instrument qualification and validation in meeting regulatory requirements. The role of HPLC in tandem with mass spectrometry and other detection methods for assaying biological samples does not receive nearly as much attention.

Assessment: The book is clearly superior to the many books on HPLC methods development which do not address pharmaceutical issues to any great extent, if at all. There is generous use of figures and tables throughout and very little overlap across chapters. Weighted Numerical Score: 88 - 3 Stars"

About the Author

Satinder Ahuja obtained his Ph.D. in analytical chemistry from the Philadelphia College of Pharmacy and Science. He serves as adjunct research professor at Pace University and is a consultant to pharmaceutical companies as president of Ahuja Consulting.


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